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Synthetic exogenous recombinant human growth hormone used as an anti age treatment was popular in USA and Europe ever since the late eighties. In the first decade of the 21 century many rejuvenation clynics sprung up around the globe offering HGH anti age treatment. Nowadays all the GH available in the market is synthetic, there are no cadaver derived versions any more.
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Human growth hormone affects the human body in many different ways. Naturally growth hormone is secreted from the pituary gland following it's way through liver (and other tissues) where it triggers insulin like growth factor one dubbed IGF1. IGF1 than uses the blood flow to reach other tissues. IGF1 is used by HIV patients to prevent muscle wasting and more recent studies have proven, that there is more to it's effects than than simply liver producing IGF1. GH effects bone density and growth of organs which is the effect of IGF1 in the blood stream, when IGF1 reaches the organs, bones and muscles it causes anabolic growth. HGH is also responsible for increase of binding proteins production and affects the cells that produce it as well as the cells next to it, the latter does not depend on the blood flow. The muscle growth is the direct result of IGF1 produced by muscle cells, not being flown there from the liver. When exposed to IGF1 the muscle satellite cells that are otherwise in a dormant state divide and change into full blown muscle cells. IGF1 also has another interesting property, it is suitable for site injections, so many bodybuilders use this drug to improve lagging bodyparts. HGH is usually used with anabolic steroids and cytomel to take the effect another step further. Wheather or not HGH is the proverbial fountain of youth is still to be decided, but so far no product has matched HGH influence on rejuvenation of tissues including human skin along with fat loss that alowes the user low bodyfat even when cheating on his diet.

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